A lame ass dude or chic. One who is lame and/or a lamer. A buster, skeezer or weirdo.
"Quit being a lamazoid Brian and let me bang your sister. Hit the blunt you lamazoid."
A buster. A lame ass motherfucker.
"Dude, quit being such a lameazoid and hit the blunt you puss ass dude!"