Becoming dangerously drunk/drugged beyond all recognition. Usually a 24 hour + sesh that has resulted in general loss of the ability do do anything other than smoke or drink, extremely diminished intelligence and zero concept of time it's self.
Girl: Yo, where were you all week? I've been trying to get hold of you since Monday!
Boy: Woah, if only I could remember! We had one serious sesh at Danny's where I'm pretty sure I lost my mind as well as my eyebrows. I'm never drinking again. Majorly danger wankered.