The feeling of
vertigo and
nausea that some people get while playing, or watching others play, 3D
FPS games, such as
Wolfenstein 3D, for which it is named.
It is more generally known as simulation sickness, a form of motion sickness. The prevailing theory for the cause is that the illusion of motion created by the virtual world, combined with the absence of motion detected by the inner ear, causes the brain to infer that one is hallucinating from toxins. The brain responds by inducing nausea and vomiting, to clear the supposed toxin.
Ingesting ginger root products (herbal capsules, lozenges, tea) may offer some relief from the
nausea.