Zyst

A cyst that also has many of the same characteristics of a zit. Often seen as a large raised redish area on the skin.

Elliot wants to pop the zyst on his neck, but he really should see a doctor instead.

by DoWhat? August 25, 2009

The crappy new name of RSC king/queen Mystress.

"Mystress' new name sucks...who would want the name Zyst?"

by ~ December 17, 2004

zyst

n. A giant, angry, throbing, pus-filled bump; part zit, part cyst

My blind date was a nice enough guy but, I was fearful that the zyst on his face could erupt at any moment!

by tboone March 13, 2010