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1.
Once spoken by an anonymous african american from New York, it is a slang word for the green leafy substance, marijuana.
*exact quote:
"I smoke a lil' tweeze now and then."
by Robbie R August 13, 2007
 
2.
a wild variety of psilocybin mushrooms (hallucinogen)
Person1: Ay you got the hookup for the tweezes...
Person2: Yea let me get that for you.
Person1: Fasho.
by ashhleywils August 15, 2012