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15.
basically an hore or slut a female who has sex with many guys
yo you know dat girl down da street?

yea man she a whole tweaker
by dabullty December 09, 2009
118 122
 
16.
Slut,whore,yooker,bobblehead
Your girl is a tweaker everyone bust her ass
by jkgggk September 16, 2009
46 50
 
17.
Someone who constantly worries about a situation and obsesses over the possible outcome of something before it happens. Someone who thinks a lot and dwells on things a lot.
I am worried about how my dress will fit, will he think I am fat?

Do you think I will get in to trouble? I am tweaking on the situation.

What will happen if the judge sends me to jail? I am a tweaker.
by kelsmaster August 09, 2009
6 10
 
18.
1. A person that's like a hoe

2. Some one who will talk to alot of females/males at once

3. Some one who's addicted to drugs
"Yo, you a tweaker for real"

"shut up tweaker!!"
by Philly Girl_14 June 19, 2009
15 19
 
19.
a whore, a promiscuous female who engages in sexual activity with a lot of people who they have no relationship with.
"man, she'll let anybody hit, she a tweaker."
by k_milly May 10, 2009
35 39
 
20.
someone who abuses methamphatamine.

usually skinny because they dont eat.
dark circles under their eyes because they dont sleep.
can harldy stand because most of their blood viens have collpased from constant injecting,

they transform themselves into a hermit-like state and keep to themselves while trying to have a normal life.
kid 1: i think that jon is using meth.
Kid2: yeah i definatly think he is a tweaker
by lovebabefor April 08, 2009
61 65
 
21.
A person who uses meth and staying awake for days at a time thinks their focused on there project usually something they think they can repair but in reallity they end up breaking it so the parts end up in a box with all the other tweaker parts
He has been up for days tweaking on electronic items , and hasnt fixed any of them , all he has now is a bunch of parts, he is such a tweaker.
by Kimberly Delgado July 10, 2006
70 74