Best used as a negative adjective when describing what you hope will result in a relationship, situation, or vacation.
I hope it goes tits up in Corfu.
by mggiedixon August 22, 2009
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"You're going down, man, tits up.
by Reddog500 August 8, 2006
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Denotes a symbolic congratulatory salute from a group of females. Used by female teams.
Cathy got red carded last night after a scuffle with that pushy witch on the other team. Hats off, three cheers, and tits up to Cathy!
by jrkfrsf July 25, 2009
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Tits up can refer either to:

1. In the case of posture, this refers to the woman lying on her back: i.e.: supine.

2. In other contexts, it refers to something broken down or in a state of disrepair.
Context #1:

She was tits up; ready and willing,

Context #2:

My old Studebaker finally went tits up: good for parts only.
by Angel of the Morning April 24, 2021
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Verb.
To head over to somewhere.
I'll tits up later and come and join you.
by LondonBird December 2, 2011
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Expression to describe when a person or activity has run its course and met its end. Dead. Finished. Done. The expression is thought to have originated from military pilots when reporting from the air the visual status of other planes that had gone down and met their end, and in doing so on the way down or at their final resting place (or both), were often times "upside down" with their wheels pointing up rather than down as they operationally should have been. When seen from high above upside down with belly and wheels pointing up, they were described as they appeared....."tits up".
Hey...are the Cowboys going to the Superbowl or not?

What? No man....they lost last Sunday. It's over. They're tits up dude.
by DallasBB May 9, 2011
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