The Pit Hole Of Hell, A Company that leads you on and doesn't appreciate your dediction and never recognizes you for your accomplishments
Sykes Sucks!
by Employee December 31, 2004
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Besides it's actual meaning, there was an oldschool rapper named Syke. He was one of Tupac Shakur's greatest friends and appeared in serveral of his songs. He's most famous for singing in 2Pac's songs "Picture Me Rollin'" and "How Long Will They Mourn Me?"
So day after day, ride after ride, we'll all hook up on the other side. Watch over your family and your newborn. Till we meet again homie.

-Syke, in his tribute to Kato
by Wes Schaller December 20, 2006
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A misspelling of the term "Psych". Most often used by people who have no idea what the term actually means, and only a loose grasp of what the appropriate context is to use the term. Also misspelled "Sike"
Brody: "Your mom blew me last night!! Syke!!"
James: "I'd have to believe it before you could actually Psych me out. I bet you'd spell it with an S too, wouldn't you?"
Brody: "Whatever, faggot. You SO believed it!!"
James: "Stop breathing my air."
by AutomaticJack July 29, 2015
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A fat, white blowfish from shark tale who can’t do it
Ay ay ay, don’t sweat it Sykes, a lot of white fish can’t do it
by Hero00003 October 7, 2018
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a common misspelling of "wordpsyche"
"you're hot... Syke!"
"you moron, it's spelled psyche!"
by Prophet August 21, 2003
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A name that describes a MASSIVE serial pervert.
Man, did you see that Sykes the other day? What the hell was he doing in that dark alleyway with no trousers on?
by Tony Regis, Ohio September 16, 2009
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