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22.

1. to add alcohol or any intoxicating to a drink that does not have any when first purchased.

2.to rise to a high level quickly

3. to strike a volleyball upward so that it is more likely to hit the ground
Someone tried to spike the smoothie mix.
by The Return of Light Joker October 29, 2008
6 4
 
23.
a syringe, used to shoot up
I need a clean spike for my next shot
by notnomore November 25, 2006
8 6
 
24.
When you're banging a chick an slip out, then "accidentally" slip it in her ass while re-inserting!
That crazy bitch was was goin so buck-wild, she almost broke my dick! So I retaliated by spiking her!!!! OR.... Sorry babe, didn't mean to spike ya, but I got carried away!!!!
by JOKES14 June 28, 2011
2 1
 
25.
To withhold a newpaper story.
Sorry, your story was spiked. Too controversial.
by Scoop's May 05, 2007
4 3
 
26.
a vampire that likes to drink and hurt Angel. He was on the series Buffy, then later moved to Angel (The greatest show ever)which was recently cancaled...did I mention he likes to drink.
the Angel says...SPIKE!!!
the Spike says...OH, bloody hell!
by um...Me June 07, 2004
39 39
 
27.
A vagina or pussy

As heard in Bruno.
Get on your knees bitch, and suck on my spike.
by Ich Ben Bruno June 14, 2010
3 4
 
28.
to spike is to hit a high point, like the spike on an earthquake seismograph it stands out (up) against the general ups and downs of the daily grind. To peak, reach a peak.
Hey, that party really spiked!
by Karl Yurangu September 23, 2007
1 2