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uh-oh spaghetti-o's 

An exclamation made after the realization one has fucked up beyond repair.
Dude, I just shot your mom! Uh-oh Spaghetti-oh's

uh-oh spaghetti-o's 

(N.) Homer Simpson's (II) Catch phrase in the short-lived Fox Dramedy, "Police Cops." Originally, a suave, stereotypical Policeman, Homer Simpson (II) was retooled into a fat, bumbling, Chris-Farley-esque doofus, who's catchphrase was always "Uh-Oh-Spaghetti-O's!" which was taken from the pasta of the same name.
Homer: "I just helped out in the Toys-for-Guns program."
Chief: "Homer! It's Guns-For-Toys!"
Homer: "Uh-oh spaghetti-o's"
uh-oh spaghetti-o's by G-Union November 25, 2003

uh-oh spaghetti-o's 

cop: "Sir are there any drugs or any weapons ion your vehicle that I should know about?"
me: "No sir!"
cop: "HOLY SHIT there is over 10 punds of weed in your trunk"
me: "uh-oh spaghetti-o's!!!"
uh-oh spaghetti-o's by MetalHead November 23, 2004

uh oh spaghetti o's 

usually when something goes wrong or you just started having drunken sex to realise its your sister!
"i think ive caught my scrote in my zipper " "uh oh spaghetti o's"!

Spaghetti O's

The only food real dank memesters eat. Especially DANK DORITOS and KINKY FUCKERY WHORES. We run on this shit boii spaghetti O's make the hoes wweeettt
LONG DICK MAN: Spaghetti O's are pretty good
Hoes: OOhhh I'm wet

Hotplate full of Spaghetti O's

Bro come on over, I've got a hotplate full of spaghetti o's just waiting to be smoked!