A slice of pizza
yo dawg, im pretty hungry, lets go to the pizza place, i could use a slice of cheese right about now.
by Stallion April 15, 2004
A womans vagina

Also used as a collective for women
Ex 1. Would't mind a shot of her slice

Ex.2 Any slice there last night?
by fat ronaldo April 21, 2010
to take a long, smooth hit (preferably weed) from a bong/vape/etc
"yo i just took a huge slice"

"that was a ridiculous slice"
by toked prophet October 14, 2009
n. Short for homeslice, a variation of homeboy similar to homeskillet, homes, homefry, homesnack, homesizzle etc.
A familiar friend. A slice of home. A Pimp.
That's a sick bass riff, Slice. Did I teach you that?

That's cool Slice, if you get fucked up you can crash on my couch
by migzi April 14, 2008
The smallest/shortest individual in a circle of friends.
"Shut the fuck up slice, some bitch mistook you for a midget!"

"Alright wait here slice while we go ride this rollercoaster. Actually, grab us some nachos while you're waiting."
by Jack N March 19, 2007
The act of saying "Bye" as in "PEACE"
"Yo you out? aight slice."
or

"Slice out bro"
by Barx November 28, 2006
originated by Brandon...also known as a "credit card"
Slice is when your friend sneaks up from behind you and stiffens up their hand and makes an attempt to slice their firmly straight hand through the victims butt crack.
Lynn: I was walking down the hall after government and Ashley sliced me! Then Zach came up and sliced her!
by Sheebs December 13, 2004
To make out with or desire to make out with.
"Oh my gosh, what a fox! I soo want to slice him!" or "He's soo slicing!"
by Jamie June 24, 2004

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