1. a combination of the words "sicko" and "fucko".
2. usually a creepy kind of person who partakes in sick or weird acts of sexual gratification.
The other day i caught my brother jerkin' off to some porn online of a guy getting spanked by some big bodybuilding bitch. What a sicko fucko!
by S-F December 2, 2010
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a word describing the most disgusting person, word, saying, or action.
person #1: (Sneeze dramatically without covering mouth)

person #2: cover your mouth, you sickening sicko! Jeez! this is why swine flu is spreading, because of sickening sickos, like you, who don't cover their mouths when they f*@#ing sneeze!

person #1: (guiltyly) sorry.
by codenamejester May 17, 2009
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Gasping for air at a concert.
"Hey Josh did you go to that Travis Scott concert, Yeah I went Sicko Mode with eight other people, I was the only survivor.
by SupperatedCooch November 15, 2021
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dont give a shit, wanting to be left alone and not fucked with.
i was in sicko mode all summer, no relationships at all.
by loaaaaadddiiiiinnnnggg October 23, 2018
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When you do something epic or ballsy.
Driver: oh shit, there's some kids crossing the road, time to go sicko mode
*Proceeds to rapidly accelerate*
by Samueliscool223 February 23, 2022
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Karen: After I took the kids I got into a really good song!
Carol: Spill the deets gurl, what song is it
Karen: Sicko Mobamba
Carol: 🗿
by Oof Daddy 69 January 11, 2019
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An action or state of being that implies rambunctiousness, or god like energy or intelligence
“Whoa, look Anthony’s gone sicko mode
by Milk chocolate swag March 16, 2019
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