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1.
A condition peculiar to high school seniors, hence the subword "senor" in senoritis. Symptons include a general apathy towards classes, homework, future i.e. college applications, restlessness and a "cannot do" attitude to surmountable school load.
Ever since Johnny complained about having Senoritis, his grades have been slipping greatly. I wonder if he can make it for the graduation.
by ocdsufferer September 12, 2006
 
2.
The disease most seniors get when about to graduate from highschool. Results in bad grades, slacking of, or incesent partying.
1. "Man, how did Carol fail that test? She's a straight A student."
"Oh, I think she just got a bad case of senoritis."
by mi. April 08, 2008
 
3.
A rare form of obsessive-compulsive disorder where the afflicted insist upon wearing a sombrero and playing mariachi music
kid: oh noes, grandpa gots teh senoritis!
grandpa: move aside chico and pass me the tequila~
by Tentacle Mike May 17, 2006