Top Definition
a holy or sacred place; a retreat or private place; Derived from Latin word sanctus
I had a wonderful time creating my own sanctum this weekend.
by Freelover April 05, 2010
Another name for one's taint, the area between the reproductive organs and the anus. A combination of "Sack/Scrotum" and "Rectum".
I sometimes forget to wash my sanctum.
by lalaveg03 January 30, 2011

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