Top Definition
"Pustulence" is a combination of 2 words (like "smog" is from "smoke" and "fog"). "Pestilence" (a devastating epidemic disease) plus "Pustulation" (the state of having pustules - pus-producing elevations of the skin).
In David Lynch's Dune, Baron Vladimir Harkonnen found pleasure in his own pustulence.
by Mike Baker August 23, 2005
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