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3.
When you're playing baseball and you get a pitch too good to not take deep.
Piss on it, turn that sumbitch yellow
by Colin July 15, 2004
 
1.
another way of sayin, screw it or fuck it
chick:lets go somewhere
dude:i dont wana
chick:pleezzz, i luv ya!!
dude:piss on it, letz go
by Totally pissed of teen July 13, 2005
 
2.
Forget about it; to do something later.
Person1: I can't go out tonight, I have to study for a test.
Person2: Piss on it. Let's go.
by Mike February 25, 2004