Top definition
Pill-up is what older women do when they have to interact with their ex-husband. Ex-husbands just drink and swear to deal with the bitchy, pilled-up ex-wife.
My step-mother likes to pill-up when her ex-husband comes in from out of town. I wish she would just smoke pot and drink a lot like the rest of us.

I found my step-mother digging through my purse and stealing my migraine medicine. "Oh I guess Thomas is coming to town," I said. She nodded and took a double dose.
by CyAdora September 22, 2010
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