Top Definition
(n) 1. The progressive loss of higher mental functions, and eventually motor skills, due to overuse of one's love muscle for thinking with.

A highly infectious condition spread by exposure to hot chicks, who are asymptomatic carriers of the disease.
Bob: As I was saying, infection of the lymphatic vessels may cause thickening of the skin and enlargement of underlying tissu... WOAH, BOOBIES!!1! .... Huh?

Bill: Oh noes. Another innocent, struck down in his prime by rampant penility. Where will it ever stop??
by Et tu, Spongebob? July 06, 2011
Humiliation felt as a result of exposure of one's miniscule penis
We were in the showers, and feelings of Penility overwhelmed me.
by xxxx December 10, 2003
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