1 - Ohio State University
2 - osu!

Ohio State University is a random university in Ohio duh
osu! is a rythm game, there are 4 gamemodes, osu!, osu!mania, osu!catch, osu!mania, all of these are hard in their own way
Matt: i study at osu (ohio state university)
Nathan: i was the greatest osu player (osu!)
by ofrfr December 14, 2020
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a rythm game for weebs, otakus, hikikomoris and lolicons which want their favourite loli anime opening to be played by a random stranger. Other definitions for Osu are ; cancer, aid to suicide or a reason for suicide
Man i really wanna die dude...
I know man i play osu too
by TheOsuGod November 16, 2017
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World's largest community college... located in Ohio.

A.K.A. TOSU, OSCC

Dear Buckeyes - "A.K.A." stands for "also known as"... the "k" is silent.
"My pappy says that I aughter go ta college, but I can't read too good."

"You should go to THE ohio state university."
by M Go Blue April 3, 2005
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Oswego State University - In up sate New York on the shore of Lake Ontario
OSU, Home of the Lakers
by Aaron Spencer August 9, 2006
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There are three major OSU's out there.

OSU or tOSU = The Ohio State University
oSu = Oklahoma State University
osu = Oregon State University
The lesson learned from this is don't go to any of these OSUs.
by kevin4cardinals January 4, 2005
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Osus is the reversed word for suso, in English boobs.
Jacqueline's osus is big.
by jakolen February 25, 2020
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On stage urination. When someone who is on stage performing decides to urinate right there.
by Amy Ger December 2, 2007
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