Top Definition
Osu
(usually pronounced: oos )

A term used in karate or mixed martial arts schools meaning yes, hello, goodbye, and I understand. A general affirmative.
Teacher: Is everybody ready?
Students: Osu!
Teacher: Begin!
by Guildenstern14 November 12, 2009

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Photos & Videos
osu
Ohio State University

The home of the 2002 Ohio State National Champions.
by James Carpenter March 19, 2003

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Osu
osu! is a freeware rhythm game originally for Microsoft Windows. It is written in C# on the .NET Framework. The game has also been ported to Mac OS X, iOS, and Android. Its gameplay is based on commercial titles including Osu! Tatakae! Ouendan, Elite Beat Agents, Taiko no Tatsujin, beatmania IIDX, O2Jam, and DJMax.

Despite the stupidity stupidity of some; it is pronounced Oh-Sue. Not OOS.
A: Have you heard that game, osu?

M: Yeah it's like guitar hero except you pick the songs.

A: Wow sounds cool. How do I say it?

M: Oh-Sue.
by Oh-Sue September 06, 2014

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osu
A Japanese Word meant to show respect. It's used for evens like Karate before the fight.

"OSU" pronounced like "os".
Osu - Let the fight begin
by James Laserbeem August 26, 2005

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osu
A term used in Karate

or

A popular rhythm game.
1. Fighter 1: Are you ready to fight?
Fighter 2: Osu!
2. Tom: What are you doing Simon?
Simon: Playing a game. It's called osu. Wanna try it?
by 123adi May 14, 2016

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osu
Oklahoma State University
OSU is a tight univeristy!
by Dizeb November 01, 2003

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OSU
On stage urination. When someone who is on stage performing decides to urinate right there.
I didn't know Fergie liked OSU
by Amy Ger December 01, 2007

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