A rhythm game capable of making you feel all stages of grief at once.
The gameplay mechanics involve clicking circles to the beat of the music, and once you enter 4* difficulties you will start to develop tendonitis, RSI and carpal tunnel at the same time.
Me: I just took part in an osu! Tournament.
Friend: cool! How'd it go?
Me: well, I can't feel my wrists and also I'm in an ambulance
by Djchu March 21, 2019
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A term used in Karate

or

A popular rhythm game.
1. Fighter 1: Are you ready to fight?
Fighter 2: Osu!
2. Tom: What are you doing Simon?
Simon: Playing a game. It's called osu. Wanna try it?
by 123adi May 13, 2016
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Ohio State University!
Probably not the infamous rhythm game that makes you easily get the carpal tunnel and other wrist and hand problems
Fren: Hey, wanna play osu?
Me: uhhh... sorry! I'll pass, I can't play in osu rn, I'm having a test in osu!
by woolf🦊 December 14, 2021
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An incredibly hard rhythm game which involves clicking on circles, dragging your mouse across tubes, and spinning your mouse rapidly across the screen.

Playing any map above 5 star difficulty is a great way to get carpal tunnel.
To this day I have no idea how people are able to clear “The Big Black” in osu! without feeling extremely lightheaded and then passing out.
by nlolhere March 1, 2021
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that rhythm game where you click circles
"instead of giving you better accuracy it just makes you better at the game"

-tokaku
person 1: hey do you know "osu!"?
person 2: yes i play with mouse
person 1: i play with drawing tablet
person 2: *gasps*
by quinetn January 8, 2022
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osu! is a freeware rhythm game originally for Microsoft Windows. It is written in C# on the .NET Framework. The game has also been ported to Mac OS X, iOS, and Android. Its gameplay is based on commercial titles including Osu! Tatakae! Ouendan, Elite Beat Agents, Taiko no Tatsujin, beatmania IIDX, O2Jam, and DJMax.

Despite the stupidity stupidity of some; it is pronounced Oh-Sue. Not OOS.
A: Have you heard that game, osu?

M: Yeah it's like guitar hero except you pick the songs.

A: Wow sounds cool. How do I say it?

M: Oh-Sue.
by Oh-Sue September 6, 2014
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(usually pronounced: oos )

A term used in karate or mixed martial arts schools meaning yes, hello, goodbye, and I understand. A general affirmative.
Teacher: Is everybody ready?
Students: Osu!
Teacher: Begin!
by Guildenstern14 November 13, 2009
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