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1.
expletive phrase. The adding of -izzle to the end of "omg" to add emphasis to the expletive meaning.

Used especially in conjunction with "fo shizzle" directly ensuing the phrase.
Person A: Do0d, you just got BEAT by the chick!
Person B: omgizzle! I suck ass, yo.
by Shifty Eyed Goat June 07, 2004
 
2.
when you're feelin like a g and instead of saying 'omg' like boring people, you say 'omgizzle'. the second you say this you turn into a re-incarnated form of Tupac Shakur just because you added the 'izzle' it makes that much of a difference.
Guy #1- Hey, did you hear that Kayne is a gay fish?

Guy #2- No way! OMGIZZLE!
*Mystical Clouds Appear*
Guy #1- Tupac?!?!?!?!?
by cookielips565656 July 17, 2010
 
3.
Oh My God! street-style
OMGizzle! Did you see tha booty on that ho?!
by jwood786 February 19, 2008
 
4.
It basically means "omg" except for with an "izzle" at the end. This word is very clean and use able
OMGIZZLE! IT'S A PICKLE FACTORY!
by PickleFace10000000 December 06, 2010
 
5.
O-M-G-IZZLES meaning omg that tickeld my tummy its often used when something seroious or funny happened usallay used by valley girls its feel good on your tounge : )
person 1: hey did you hear lydia got the lead in the school play

person 2: OMGIZZLES
by gurl1234gurl1234 June 04, 2011
 
6.
an expression of great shock or disbelief or excitement
omgizzle! i won an iPod! =D
by SammyTheSnake December 12, 2010