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1.
To defeat by an overwhelming margin.
Our Little League team got murderlized in the playoffs.
by J. McCrackan August 05, 2005
 
2.
Excessive murdering of someone or something
"damn he really murderlized that steak"
"i'm going to murderlize yo ass"
by oyizzle November 07, 2007
 
3.
To defeat or destroy a person or a group of people when fighting for something you believe in. First said by Tum Tum in the movie The Three Ninjas one of the greatest series of movies of all time.
Tum Tum: "Lets murderlize them!"
by gootch420 August 11, 2010