n. Pharmaceuticals courier.
Dude, Pedro the mule just checked in. Let's 420 !
by D'emon November 8, 2002
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The complaining noise a mule makes during stressful work.
A cross between a whinny and a bray.
(Old-English style threat from a recent popular film)
“I wont touch Barton. Not until I make him kill you. Slowly, intimately in every way he knows you fear. And then he’ll wake just long enough to see his good work. And when he screams I’ll split his skull. This is my bargian you muling quim. ”
by Geedud May 4, 2012
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to be "owned" or dominated; usually over the internet or form of internet such as Xbox Live.
After posting a naked picture of Clay's fat girlfriend on the forums, Brett knew he had completely muled the insolent poster.
by Jason Harrington August 7, 2007
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a terrible shoe that appeared on the market originally in the late seventies. The shoe was unfortunately revamped in the late nineties, but quickly faded into obscurity.
by Jesse Valencia October 25, 2002
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To carry, in one's anal cavity, any contraband, i.e. illicit drugs.
"Jorge muled the baggie of yeyo across the US border, but his anus hurt afterwards."
by Anthony Jaketti February 3, 2005
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A word used to describe something disgusting.
Person A: Did you get a look at her face?
Person B: yeah, she's MULE!

Person A: I just threw up!
Person B: That's MULE!
by omso January 29, 2011
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Someone that is generally incompetent. Opposite of a thoroughbred.
I don't know how the new director got his job. He sure is one dumb mule.
by thaddeus February 5, 2004
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