Muff (M.U.F.F.) - Mandatory Ugly Fat Friend. Something that follows every hot girl in order to make it difficult for you to enjoy your time with your hot friend. They are never enjoyable to be around; a muff's only purpose is to make it difficult to game on the hot girl you like.
You: Man, I'm definitely hanging out with Marissa tonight!

Friend: Too bad her muff will be with her!

You: Are you serious?!?!? I hate Brenna! She's definitely going to Cock Block

Friend: No one likes a muff...
by afrotreetrunk February 23, 2012

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Back in the 90's this word meant being smacked upside the forehead when you least expect it.
Boy 1: Hey, want to see something cool?
Boy 2: Yeah.
Boy 1: Muff.
Boy 2: Ah! What you do that for?
Boy 1: HA HA HA! You walked right into that one.
by Falap January 28, 2010

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Extreame messup, "To fuck up something", to blow something (hahahaha not tht way You no waht we mean)
Oh watta Muff!!

Dude you muffed that pass!

Oh MUFF
by Lil Nait234 January 17, 2010

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1. what you do when your fat goes over your pants/tights/skirt/bottoms

2. the verbial form of muffin top
Wow, do you see that girl? She's muffing like crazy.
by Lindsey J D August 16, 2007

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A large hairy, unemployed person with abnormal amounts of body hair. Is able to grow beards over night and grow stubble on tongue. The Muff will be able to sustain a heavy amounts of alcohol and protein shakes.
Josh is the mighty king of all Muffs. Peace x
by "Beaver" n STEVE June 03, 2007

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It is a surname. I think the name comes from Yorkshire and quite a few people from America have it as their last name!
Joanna Muff or Jonathan Muff.
by Anonymous Name April 01, 2007

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a replacement word for: drink, drunk, beer, pussy, any other drugs, and so on. pretty much is a way to keep what you're doing in the dorm room private and anonymous to the passer-by's in the halls.
Let's muff. Grab me a muff. Dude, you're muffed.
by Matt Baumann February 02, 2007

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