look up any word, like dirty sanchez:
 
37.
Of course, we call know that "mofo" is a more "polite" form of the word "motherfucker", just like the abbreviation "M.F.". "Mother" is also a substitute for that nasty word. "Mofo" is also the title of a song from the album "Pop", released by the band U2 in 1997. The song refers to Bono's mother, who died of cancer when Bono (Paul Hewson) was a teenager (Paul McCartney grew up with losing his mom in the same way). In the song Bono asks his dead mom "Mother, am I still your son?", and he asks her if she sees him on stage tonight and if she is proud of him. He does not sing the words "mofo", "motherfucker" or any related word in the lyrics. Maybe in a case of Irish humor, the song got its name as a parody of all the songs that feature the word "motherfucker" that saturated the market at the time, going on today.
1. That porno mag publisher is one sicko mofo, and he knows it, and he relishes that fact. He is proud to be an SMF.

2. When I saw U2 in concert in the spring of 1997, the 1979 classic by M called "Pop Music" was played, then came "Mofo", followed by "I Will Follow", then by several other U2 hits. Major kick ass.
by Starpunk September 20, 2007
 
1.
Short for mother fucker. A person who thinks they are the shit, dressed down with sagging pants, a high need for a belt, too much gold to make the national reserve jealous, and an attitude that stems from not having parents who knew how to refrain from the use of crack cocaine.
"Hey Dave, look at that putz...man what a mofo."
by deez nutz March 05, 2003
 
2.
1. (abbr.) mother-fucker
2. (n.) One who is hard-core
Dat man is one bad-ass mofo, yo!
by k1 October 03, 2001
 
3.
A shortened version of the word Motherf**ker. This meaning tho is meant to be non abusive, almost as a sign of respect or greeting for fellow friends..It must be stated tho that the use of the full word is a sing of abuse
Hey Mofo = Aceptable.
Hey Motherf**ker = Abuse
by rrlwat June 19, 2006
 
4.
Short term for motherfucker
Damn, that mofo is stealing the bank. Where are the shithead cocksucking police dicks!?!?!?
by Anonymous February 25, 2003
 
5.
It's an abbreviation for "Mother Fucker".
Guy - I fucked your mom.
Dude - You sick Mo-Fo!
by kane April 27, 2003
 
6.
1. Short version of the word mother-fucker
2. Industry nickname for San Francisco based law firm Morrison and Foerster. The firm still uses the domain name mofo.com for its IP network services. The firm actually rebranded itself MoFo for a while until it realized that the strategy was less than successful.
John just got a job over at mofo after graduating from Law School.
by mlu December 25, 2005
 
7.
Used as Mother Fucker. Just a fast way of typing.
The Net- "I pwned u mofo"
Real Life -"Get out of my house, you Mofo!"
by JoshTaylor August 06, 2005