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methed up 

When someone does methanphetimines so long they don't know how to behave in society. The drunk meth cook violating probation that kills a young man while she was talking on her cell phone hooking up her next victim, while driving thru town.! A destructive drug user.
methed up by JeannieHotPants March 4, 2008

Methed up 

An action or the result of an action that is caused by a meth user that's high on methamphetamine.
Bro, did you see the geekers house up the street? It's methed up!

TweekersGeekersMethamphetamine
Methed up by J Milluh September 8, 2018

METHED UP 

THE CONDITION OF BEING SO STUNG OUT THAT THE IDEA OF SELF GROOMING HAS BEEN LOST AND REPLACED WITH INSATIABLE URGE TO FIND THE BUGS THAT CRAWLING AROUND UNDER YOUR SKIN BY BURROWING HOLES WITH YOUR FINGERNAILS.
OR AN IDEA SO COMPLETELY FUCKED UP THAT IT MUST HAVE BEEN FORMED ON A METH BINGE.
METHED UP by MONGO TRAINER November 13, 2018

dang that's methed up

When witnessing an act that could only be committed by someone who has not slept in as many days as they have left teeth.
"Did you here Tom's mom asking to suck me off for money"

"No I didn't, dang that's methed up"
dang that's methed up by gisimisim December 22, 2008

Methed Up 

to be on meth while under the disco ball at cheap skate.
I'd choose to be methed up over the prostitutes at the front door any day

Methed-up 

How a person on meth says messed up. Wrong, aint right
Did u see her face? Thats methed-up! U really methed-up this time man
Methed-up by Thottie2Hottie October 8, 2017