Comes from the movie Scarface, where Cubans pronounce the word "man" as "mayne".
You chicken mayne...you almost made it.

Hey, hey, hey, FUCK YOU MAYNE...who put this thing together? Me, that's who.
by asd September 2, 2004
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Mayne: a word that is most frequently used by actor Terrance Howard
Wasup Mayne it’s me Iron Mayne.
Hey mayne you got my money mayne?

Have you heard Gucci Maynes new joint?
by My Neeg June 9, 2018
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Mayne is a Southern term used the same as sayin 'man.' Its in alot of Crunk Songs.
'Yea mayne' or 'What up mayne'
by Shae September 2, 2004
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different way to say "man" , orginating the spanish accent of saying man
by vh_bkbombshell April 28, 2005
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'Mayne' is a better/ghetto term of saying man.
Examples:

One- "Mayne, she was good last night!"
Two- "Oh mayne, you nearly ran me over!"
Three- "Sup mayne?"
by Sickbitch. May 10, 2011
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Regional pronunciation of the noun "man," often in the American South -- though it appears frequently in Chicago blues music, and particularly in the songs of Muddy Waters, where this pronunciation can be clearly heard.
I'm a mayne!
A full-grown mayne!
I'm a lovin' mayne!
-- Muddy Waters, "Mannish Boy"
by Mel Sharkskin June 8, 2006
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