Also known as Bovine Spongiform Encephalitis (BSE). It affects the brains of cows, and somtimes sheep too.
I wish curry would get mauled by a cow with mad cow disease
by Evil Tim September 21, 2003
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When someone is so stupid they sound like a cow with aids when they talk
The homeless man was trying to tell me that but he had mad cow cancer
by Invention20k May 13, 2015
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Mad Cow Disease is when fat people run around trying to eat you.
HOLY SHIT that bitch got Mad Cow Disease.
by Nire November 20, 2003
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a fatal disease that affects both humans and cows. very talked about.
one damn cow was found with mad-cow in canada and everyone banned meat.
by megan March 4, 2004
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something PETA planted in our cattle in an effort to turn everyone to vegatarians/vegans
damn PETA now they are trying to kill meat eaters with mad cow disease
by kick petas ass January 4, 2004
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1.Used to categorize an affliction that turns a normal woman into a mountainous, sloppy looking woman with a snub button nose and a haircut that was crafted with a lawnmower. Usu. gotten by having low self esteem, recreational drug use, poor diet, and lack of intellectual stimulus.
2.Any other similarly or un-similarly described fatter female afflicted with this ailment.
Ex1: Friend1-" What in the hell happened to her?!"
Friend 2-"You didn't hear? S'shame. She developed Mad Cow Disease..."
Friend-1 "Fuck!"
by TooTrue August 26, 2008
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A description for a girl who has a butterface and a bad personality, making her appear as a cow of sorts.
Damn that girl has mad cow disease, she's such an ugly bitch!!!
by CheefQueefQueens69 May 12, 2022
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