Top Definition
in the same vein as "go forth and multiply", "piss off", "fuck off" and so on...

origin: warrington, england
...will you please knob off, dickhead...
by critch April 13, 2005
3 more definitions
British Slang term meaning fuck off, piss off, wank off, toss off, or go away.

The term originated in Manchester, England and is very popular there. Most people use this term at least once per day.
C: Hey, do you fancy a chat?
K: No. Go knob off, you bellend.
by Big Boy P January 26, 2015
To masturbate, fap, jack off, wank, me-time, choke the chicken, spank the monkey, beat the meat, squeeze the cream, charming the snake, manual stimulation of the penis.
"Gonna go knob off for a bit", said Jeff.
by FilthyHobo420 June 12, 2012
a particularly un-arousing experience

a floppy cock

an un-erect penis

opposite of knob on

U.k. (slang) Tell someone to go away
seeing my brother with my moms dildo gave me such a knob off

I have such a big-ass knob off right now

Knob off you little twat
by Tom P. Cock March 31, 2006

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