look up any word, like fluffer:
 
1.
Something you say when shit is off the wall, comparable to saying thats sick, awesome, dirty, rad, insane.
A skater pulls of an unreal trick, you would say, "Man that shits infected, so infected its pussin."
by Kevin McR December 04, 2007
 
2.
Something that has changed from good to bad, likable to unlikeable, usually referring to a person. Often, there is the possibility that said person is now a jackass because he has been replaced by The Thing.
MacCready and Palmer are friends. Palmer tries to kill MacCready and all of their other friends in their cool snow-fort.
Palmer is said to be infected.

Lynch and Larry hang out a lot. Larry stops calling Lynch for no reason. Larry is said to be infected.
by Hartwell June 24, 2006
 
3.
One of the best songs in the history of Punk Rock Songs!!
Dude, my friend can play "Bad Religion - Infected" on the drums!
by Luke July 08, 2003