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Hooked Up 

When 2 people kiss and/or fuck.
I agree, it depends on your region.
'I hooked up with your sister'
Hooked Up by Diego November 12, 2003

hosed up 

To be completely messed up or ruined; FUBAR-ed (fucked up beyond all recognition)
hosed up by dHALL November 3, 2007

holed up 

Sitting at your PC - day and night - in the dark in your jammies without any human interaction.
Bob was holed up all week playing doom. He needs to get a life!
holed up by Danielle November 16, 2004

hooked up like a dumptruck 

to get a lot more than you pay for or expect due to the kindness of someone else looking out for you.
Bono- " did you get that dime bag?"

Me- " yeah, it's hooked up like a dumptruck"

Bono- " holy crap that's the fattest dime bag i've ever seen!"

Hooked up 

Nobody knows exactly, can be anything from holding hands to having anal sex. Pretty sure it drives most normal people insane
Bro: yo did you hear, hoe from our school hooked up jock?
Me: No. What did they do?
Bro: They hooked up
Me: Okay but bro, like, what the FUCK DID THEY DO?
Bro: How the hell should i know, i just heard they hooked up! fuck

(and now i searched for what it means on UrbanDictionary.com and still couldn't find an answer)
Hooked up by Bob Marusi October 10, 2011

Hooked Up 

Hooking up with someone, making out with them, but not going all the way. Regional usage; note that "hooking up" may mean you went all the way in some places.
"We hooked up last night"
"John and Katie hooked up at the party"
Hooked Up by your mom March 10, 2003