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1.
Interviewer: Dick Cheney, do you wear boxers, or briefs?
Dick Cheney: Depends.
by Agnos Morehead August 05, 2006
 
2.
1. Padded undergarments used to minimise discomfort and embarrassment of sufferers from weak bladders.

2. May also be used during intense moments of laughter.

3. A call-out term after hearing a funny joke.
Depends! Depends! (That was funny. Please bring me my Depends before I wet myself).
by Amy August 22, 2004
 
3.
Diapers for the elderly who have lost control of their bladder due to old age. (Can also be used figuratively to make fun of someone with a small bladder or someone who frequently wets their pants/bed.)
"My grandma told me to get her something useful for her birthday, so I got her an economy size package of Depends. She was thrilled."

"My algebra teacher is a bitch and wouldn't let me go to the bathroom more than once during class. I think I pissed my pants!"
"Girl, you gotta get yourself some Depends!"
by anonymous January 09, 2005
 
4.
Some big ass diapers!
We went to the store the other day and saw some fatties buyin Depends!
by 0celloman9 July 26, 2008
 
5.
A specialised type of pad used by elderly women in case of bladder leakage.
An example of one of the commercials :

Dolores: Fack Edna, I'm pissing like a racehorse!

Edna: Well grab yourself some Depends, bitch! We gotta go get all up in that at the club!

Dolores: Fo real!
by Joel April 13, 2005
 
6.
Indian for, I wore my sexiest lingerie and asked you to be my wife.
I wore my depends today.
by Dick December 25, 2005