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"Son of a..."
It's a shortened version of hijo de puta (“son of a bitch”).
Glottis: We have to find the key!
Manny: Hijole!
hijole by Master Speed November 3, 2016
Asombro
hijole! se acabaron las caguamas
hijole by egnatius504 August 17, 2022
v. to ruin the punch line or otherwise interrupt someone else's joke
Every time I get to the punch line, she hijokes me.
hijoke by scholzilla October 18, 2009
Slang for “ his hole
Ohh hisole!
hisole by Useitwisely March 8, 2018
Australian slang. Used to start a sentence or express happiness, surprise, admiration or pleasure. Can also be written or pronounced "izole."
Hizole, I'm headin' out yarrabah way.

Hizole! That was a pretty chay backflip!

Hizole! I wasn't expecting to see you tonight!

Hizole, did you see him skull that JD? What a chay cunt!
Hizole by Auxen October 8, 2012
An exclamation, in mexican american verbnacular that's much like "Jesus Christ!" Short version of "hijo le chingada" (son of a bitch!).
hijoley by South Fizzle Rizzle December 28, 2007