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guinea pig of one's own demise 

what someone becomes when he or she goes out on a limb to try something new or risky and ends up having his or her plan fail completely.
Theorizing that the more I studied, the worse I do on tests, I didn't study for my comp sci test and I failed. I was the guinea pig of my own demise.

In Spider-man, when Norman Osborne conducted experiments on himself that lead to his insanity and death, he was the guinea pig of his own demise.

(variations of "guinea pig of one's own demise")
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guinea pig shots 

The act of holding one's beveridge above one's head and against a wall. Then tilting the drink back and proceeding to suckle the liquid from the container as a guinea pig would water from its water bottle.
I blew so many chunks last night from all the guinea pig shots we were taking; it was a wild night.

"Dude! Guinea pig this Burnett's with me! Go Deacs!!!!"

sexual guinea pig 

a slut that likes all of the sexual postions
miley cyrus is SUCH a sexual guinea pig , she likes it up,down and side to side!
sexual guinea pig by poopie logles February 23, 2009

steaming your guinea pig

It is needed for steaming your guinea pig.

guinea pigs in my pants 

An expression that seeks to describe the overstimulation implicit in what may feel like nearly intolerable anticipatory excitement.

Guinea Pigs

Cute, cuddly,and great pets!
Guinea Pigs are cool critters!
Guinea Pigs by Shelby A April 11, 2007

Guinea Pigs

1. A small creature that children own as pets, usually called the name of their favorite condiment. Ex: Peanut butter, Mustard, Ketchup.

2. The name for a man that a younger girl is strangely attracted too. The man is older in this case.
1. Fanny Jo: I got a pet guinea pig!
Susan Mae: What's his name?
Fanny Jo: Mayonnaise!

2. Aly: Guinea Pigs is so hot today!
Lexi: EWWWWWW!
Madison: EWWWWWW!
Ana: EWWWWWW!
Aly: What?!