Gross Upper Fup, the next step beyond the first roll of fat above the female genitalia.
Her fup will become a guf, if she does not regulate her eating and get some exercise.
by JWJ August 29, 2006
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phewwww can you smell that i've just guffed!!!!!!
by marie August 5, 2003
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something that is very tuff, just like the fortnite skin guff.
yo that's tuff like guff
that was guffed
tuffington 2 like guffington 2
by GoggleSquadron January 28, 2023
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Wow George, I never realized your girlfriend had such a GUF.
by drshogie January 19, 2011
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Someone or somthing that is annoying you at the time.
"she's a stupid bitch"
"yeah, what a guf"
by Meg October 31, 2004
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Ughh, what a day. I really need a GUF, right now.
by Daezed June 19, 2014
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To COMPLETELY dominate somthing or someone
I totally guffed you up
by DFG January 14, 2003
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