When a girl talks with the same lisp that a gay guy/sorority whore does. Very common with entertainment figures and car commercial actresses.
Jay: "This girl is talking like Richard Simmons."

Pat: "Yeah man... Total girl lisp."
by 303alchemist January 14, 2014
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The insanely annoying little girl voice that immature and stupid women love to use, especially when trying to weasel shit from other people.
When Steve heard the hottie at the bar talking in a little girl lisp he knew she was going to be a pain in the ass.

“Damn it, woman, you’re 27 years old, stop talking like a fucking 5 year old! It’s just fucking sad at this point! This little girl lisp shit isn’t cute anymore, it’s just pathetic!”
by Brett Burkhardt April 27, 2008
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