15
1.Something that is Over.
2. A situration that is lost.
3.Nothing left to do.
Man! I lost the match Game Over.
His wife just caught him cheatin."Game Over"
by DE-BO July 05, 2004
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16
Phrase used to describe one who has consumed far too much liquor and is therefore reduced to a drooling, snoring, unconcious lump who may or may not end up vomiting on themselves or other people later on in the evening. May sometimes lead to boot and rally, pissing in the fridge, or other drunken acts which will undoubtedly not be remembered in the morning. See ptfo. This is the most opportune time to attempt such daring feats such as teabagging, giving a flying squirrel or other humiliating acts.
Dude, check nick out, Game over.
Woah, did nick just boot-n-rally? i thought it was game over! add another tick to the boot-n-rally tally.
by Ry-Lo September 17, 2007
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17
The hellish headache after playing 7+ hours of video games.
1: Dude, I have the worst gameover.
2: Oh damn, how?
1: I beat Dead Space 2 on Zealot overnight.

2: Jesus bro, thats hardcore.
by OrnateCocoapuff February 03, 2011
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18
the aftermath of staying up all night playing video games,with symptoms of a hangover the next morning.
i stayed up all night playing uncharted 2,and went to bed at 6 a.m. woke up at 2 with a gameover.
by ronda howard January 08, 2010
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19
when the act of slipping or falling results in fatal or severe bodily harm
dude my brother had a game over in the shower.
omg how?
he totally slipped on the soap and broke his leg.
by NRHsteezy March 04, 2008
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20
When something doesn't go your way. When a girl is not attrative. When you run out of alchol. When the subject is over.
1.You found out that your ho is pregnant "game over"
2.No way dude, that girl is "game over"
3.No beer? This crack whore party is "game over"
by Crap Weasle October 03, 2004
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21
When someone's dead, or too messed up to go on living a normal life.
-You hear about Eddie?
-Yeah I heard he od'ed on some bad coke.
-It's game over man.
by david k February 28, 2005
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