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Can be used for any sexual activity, ranging from "feeling up" and groping to violent aggravated sexual assault and rape.

Used in common context by women before going into the washroom, proclaiming they are about to masturbate.
I'd freshen her till next August.

"Imagine if that horse bucked her off and freshened her up..."
by Ringwall May 15, 2009
to treat a girl or woman with too much familiarity.
I strongly take exception to your freshening my wife every time you meet her.
by uttam maharjan September 01, 2011