Linguistically, this word has a complex origin. In simplest terms, "ese" is derived from the Greek "es" meaning "is" and "e" meaning one of Spanish-American heritage. In more complex terms, the word is derived from the Latin "E", meaning "referencing one who is believed to be spanish" and "se" meaning "american".
"You're going down, ese." - Pearl
or
Ricardo: "Yo ese, good to see you made it 'cross the border."
by Bilqis Shambles September 28, 2007

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Top Definition
The one you are refering to. Should only be spoken by Mexicans, Cubans ect. Otherwise it's like saying nigga when your white.
Get outta here or I'll shoot your ass esé.
by Cody Martinez September 30, 2003

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A fellow Hispanic, your close friend or homey, homeboy.
Hey, ese, I'm gonna let that little mamacita feel my latino heat!
by weave April 02, 2003

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all these other definitions are wrong. ese is used mostly by MEXICAN gang bangers. ESE is used by Surenos. If you believe every Hispanic ethnicity uses the word ese, then take a trip up to northern California.
there is nothing but ese's in southern california.
by rich_e_rock January 24, 2006

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Basically means homeboy, dog, dude, man, or homes. Usually used by Mexicans.
(Mexican): Que pasa ese?
(Other Mexican): Nada ese. E tu?
by HotSauce May 05, 2004

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Refers to the person you are talking to or talking about. It takes the place of words like "fool,""nigga,"and "dog" when used on the streets by youth. In 2007 it is mostly used by gang members or by people refering to Mexican American gang members, but not exclusively. The word was used long before the Mexican Mafia, or surenos, existed. Pachucos, Mexican American zoot suiters of the 1940s, used the word ese in Los Angeles, Tucons, El Paso, San Jose, Albuquerque, Gilroy to name a few documented locations. It is true that todays' Mexican American gang members from northern California, aka nortenos, refrain from saying the word ese. This is because "ese" is how you pronounce the letter "S" in Spanish and they take that as referring to "S" for surenos, Mexican American gang members belonging to the 13, the Mexican Mafia that originated in southern california but is now in northern california and other U.S. states.
Sabes que ese? (You know what ese?)
Te voy a filirear! (I'm gonna stab you)

Who popped T-bone?
It was dem ese's!
by Chicano Historian March 12, 2007

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ESE means the letter "S" which stands for SURENO or southsider. So that's why Mexicans that are surenos use it.
Yo homes most of you people are wrong. MEXICANS are the ones that use the word ESE. Some of us use it instead of saying the following:

foo,nigga,homes,leva,etc.
by Surena May 31, 2006

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What you call a fellow vato, basicaly means homeboy
whaddup ese?

f*ck you, ese!

ese! you owe me money, holmes
by Mexican-Desperado December 07, 2003

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