A pointless exclamation made by "that guy" at a party. An attempted "douche-chill" tool comment. When said, the speaker is asking to get hit in their balls.
Guy with a popped collar: Duchenne!

*balls*

Guy with a popped collar: Ow. My balls.
by Robert Fett April 22, 2011
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1. Duchenne Muscular Dystrophy. Clay Matthews appeared in television commercials in support of finding a cure for DHD.

2. Can refer to people who are clueless (such as tourists), appear to be lost at all times, people who get in the way, people who walk slow, or are just generally retarded.

3. Someone who is incredibly high and cannot function properly in a normal sense.

4. The morning after a night of excessive intoxication.
1. "Oh man, did you see Clay Matthews giving everyone the business on Duchenne?"

2. "All of these fucking tourists must have duchenne, do they really need to block the entire intersection during rush hour to look at their tourist maps?"

3. "Naw I can't go out tonight. I smoked too much and have some serious duchenne."

4. "Dude I found the Windex in the fridge this morning....one of us has duchenne"
by Tbru5T April 6, 2011
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A Devastating X-linked illness (mostly affects boys) caused by a mutation in the DMD gene which produces a protein called Dystrophin which maintains a strong and healthy muscle and prevents muscle injuries. Due to those with Duchenne not being able to produce Dystrophin, their muscles weaken overtime and their heart muscle with become so weak that their heart will just give out. Symptoms become apparent when the child is a baby as they will exhibit signs of delayed motor skills such as crawling later than other boys or walking later than other boys. When they do begin to walk, their gait will be abnormal and will tip-toe rather than put their heels to the ground when walking. As they get older, they will need a wheelchair because their legs will become so weak that they can no longer walk, this normally happens at the age of 12. Due to improvements in treatment for Duchenne Muscular Dystrophy in recent years, more people are living beyond 20 which was a rare occurrence 20 years ago, now the average age of death is 27.
It is so Devastating to see a loved one fade away as a result of Duchenne Muscular Dystrophy
by Rotten Turkey March 27, 2023
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