abbreviation for diarrhea. The result of something that infuriates you becuase it is so stupid or corny in a kind of inexplicable way. ie. couples that take pictures of themselves kissing and post them on facebook, tear-jerking commercials, the movie Garden State, Uggs, adolescent livejournals.
"this elevator music is really giving me dire."
"Oh my God, that girl's outfit is giving me massive dire!"