to eject someone from a window
"piss me off and i shall defenestrate you"
"we wouldn't want anything happening to your fenestrates now would we
by Rex Mundi January 28, 2004

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The act of throwing someone or something out of a window.
Helga: "What did you just do Bobby?!"
Bobby: "What can't I defenestrate my trash out on to the highway?"
Helga: "Are you retarded?! That's called littering, we could be fined!"
(Cue the police)
by Painthetownfred February 02, 2010

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to reduce to utter ruin or nonexistence; destroy utterly; to molliwhop something real nice
After the Mark made a comment about Sean's sister, Sean defenestrated him. Mark was last seen missing two teeth and with a nice shiner.
by Soheil Saeed February 26, 2008

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the defensive act of castrating someone in order to prevent sexual advances. First used in Questionable Content comic number 36.
I had to defenestrate my roommate before he tried to sleep with me.
by RoblingRobot November 10, 2009

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To quickly close a computer window so as to prevent your boss/girlfriend/etc. from seeing it.
I was checking out some hot girl on girl porn on the internet when my girl suddenly came home and I had to defenestrate it right quick.
by Windoze XP March 25, 2005

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To uninstall software from a Microsoft operating system, usually in frustration.
I couldn't get that program to do what I needed it to, so I defenestrated it and installed something better.
by jsgarvin September 23, 2010

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The Urban Dictionary T-Shirt

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The Urban Dictionary T-Shirt

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