look up any word, like fleek:
 
1.
1. a Mexican slang word for experienced or cunning.

2. Skill in deception; guile.

3. Skill or adeptness in execution or performance.
Es un buen peleador, ya tiene mucho colmillo.
by andres3 August 16, 2009
 
2.
One of the many variety of Cheeto snacks sold exclusively in Mexico and South America, flavored by cheese and red chile peppers. They are shaped like fangs(colmillo is fang in spanish).
Dude have you tried these colmillos their freakin good ese!
by madman89 April 06, 2006