Something that spoils or ruins an otherwise enjoyable event, esp. when in relation to ruining a drunken or drug-induced high.
Man, we were having a blast at that bar until Jim told us he was going home to do his girlfriend Cindy's laundry (and leave us no ride home). What a buzz rape!
When you have to pee in a movie but don’t want to miss anything, and must do the following mental equation: will the amount I have to pee cause enough discomfort to diminish my attention capacity for the remainder of the movie to an extent which is greater than the amount of the movie I would miss by making a mad dash to the restroom.
I saw Satantango last night, wonderful film but by the 5th hour I had to start doing pee calculus.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).