Someone or something that is aggravating. From the combination of the words "bother" and "aggravation".
That guy keeps calling here! He is beginning to be a botheration.
by Brennon Guilbeau March 07, 2006
n. An expletive so mild that it doesn't count as an expletive. Not recommended for those who don't want to appear affected, or at least a bit namby-pamby.
"Botheration! I just cut my wrist on a jagged shard of glass!"
by JohnWWells December 07, 2003