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your brother be your mother 

The supreme comeback. The five words, that if used in succession, will force the entire known universe to collapse within 4 microseconds. This is never to be used until it is absolutely needed.
Billy: Ur mom gay
Tom: Ur dad lesbian
Billy: Your sister is a mister
Tom: Your brother be your mother

*Everything instantly collapses and everything stops existing*

that would be your mother

a quote taken from a tf2 animation, involving spy mentioning scout's mother
James: ok so who broke the dinner table?
Brian: that would be your mother

Ur brother be a mother 

The ultimate, by many forbidden, one line to destroy someones will to live
Ur mom gay
Ur dad lesbian
Ur granny tranny
Ur grandpas asexual
Ur sister a mister
Ur brother be a mother
"Sad opera music plays as screen turns black and white"

That whould be your mother! 

Spy in Team fortress 2 telling Scout he banged his mother.
1 : What, Are you the president of his fan club?
2 : No, That whould be your MOTHER!

be a good mother fucker 

The famous catchphrase of the famous Aussie Legend, Isaac Butterfield. There really is no simpler way to explain it's meaning, simply put: "be a good mother fucker"
Mate: Hey Isaac, be a good mother fucker!
Isaac: You be a good mother fucker too!

Leave me in your mother (azov oti be-ima shkha) 

This expression comes from Hebrew. Although it sounds very crude in English, it's not supposed to be. the expression "in your mother" (be-ima shkha, in Hebrew) means "please" (it is also used when someone tells you something great. It's a short for "do you swear in your mother?"). So this means that "leave me in your mother" means "leave me (alone) please".
Someone: Hey, c'mon, let's have another game!
You: Ohh... leave me in your mother...