Top Definition
Organ whose only purpose is to be removed at some point in one's life.
Todd: Where's Matt?

Charlie: Matt's out today. Had to go get his appendix removed.

Todd: Dammit, what's an appendix good for anyway?

Charlie: Getting removed.
by shoppingcartman January 19, 2011
1 more definition
Someone who ruins the party; a complete loser; the opposite of "the life of the party"
Anthony is such an appendix.
by anthonyisaloser March 04, 2008

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