Southern polite people say "Yessum" to a female(usually an elder) meaning "Yes Ma'am". Can also be spelled "Yes'm"
Teacher: Warsh the chalk board and then you can go home.
Sorta like "yes ma'am" only spoken very fast.
<Mother> Shave your balls, that tea-bagging session we had last night nearly clogged my throat with hair like a shower drain.
an affirmative answer of a yes/no question; originating in Southern US shortened version of "yes, ma'am"
yessum, miss daisy i'll drive you to the store, yessum.
"Yes ma'am," common southern slang. It's a term of respect to a woman, usually older than the speaker.
"Go kill yourself, you stupid fuck."
From 1920's america, was used in the deep south by Jem and Scout in the book "To kill a Mocking Bird" means yes
Nicole - "Have you seen my boots"
Jessica - "Yessum, they're by the door"
When you say yessums, you mean "yes"
A response usually used alone in a mumbling manor to tell people that you are paying attention to them and you understand.
Jill: Can we go up the hill?