What one who works a full-time job will catch at a certain point in the week where they are no longer willing to do work in anticipation to the upcoming weekend; similar to the more popular 'senioritis' often found in high schools.
On Thursday afternoon Stacy threw down her work and said "I'm done, I'm not doing anymore, I've got a severe case of weekenditis," as she strolled off to the break room for an undetermined amount of time.
by Lizzz S August 28, 2008
A sick day on either side of your normal days off causing your weekend to swell.
I came down with weekend-itis when Friday got in the way of my three day weekend.
by Finzano07 February 21, 2012

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